2022 MHIQ Seminar Series - Unravelling the Relationship between Sleep, Pain and TBI

2022 MHIQ Seminar Series - Unravelling the Relationship between Sleep, Pain and TBI

Principal speaker

Professor Richelle Mychasiuk

2022 Menzies Health Institute Queensland Program Seminar Series

Disability and Rehabilitation Program

Presenter: Professor Richelle Mychasiuk

Title: Unravelling the Relationship between Sleep, Pain and TBI

Seminar Overview -

Children and adolescents have the highest rates of traumatic brain injury (TBI) resulting in hospital visits, with mild and repetitive mild TBI (RmTBI) accounting for 80% of these injuries. Headache and abdominal pain are one of the primary symptomatic complaints in this population. What's more, adolescents are disproportionately represented in populations at risk for sleep disturbances and sleep deprivation. Current guidelines recommend between 9-11 hours of sleep for adolescents, but they average < 7, and more than 1/3 of teenagers report falling asleep at school. Given the fundamental relationships between neuroplasticity, sleep, and pain, we have been studying mTBI-induced desynchronization of the brain's clock at the behavioural, molecular, and pathophysiological level in adolescent rats. In addition, we have explored the role of orexin and the orexinergic system in modulation of these outcomes. In this seminar, I'll tell you what we have learned.

Presenter Biography -

Richelle Mychasiuk is a professor within the Department of Neuroscience at the Central Clinical School, Monash University. She oversees an internationally recognized laboratory for the study of neurodevelopmental plasticity. The laboratory uses extensive behavioural, epigenetic, imaging, and neuropathological techniques to examine the influences of early experiences on long-term outcomes. They are particularly interested in understanding how early environmental manipulations (i.e. stress, drug exposure, diet) modify brain development and recovery from brain injury, as well as the risk for chronic pain and mental health disorders. In addition, they closely collaborate with the Gastroenterology department and the Immunology department, in the GIN hub initiative which is designed to further understanding of the brain-gut-immune axis and rapidly translate research from the bench to the bedside.

RSVP by Thursday 9 June 2022 -


Seminar Flyer -

Download the flyer for this seminar here

Microsoft Teams meeting link -




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RSVP on or before Thursday 9 June 2022 15.11 pm, by email mhiq@griffith.edu.au , or by phone 07 5678 0907 , or via https://forms.office.com/r/KSAs4LWFrN

Event contact details

Session 1

Session 2